Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Can you take plaquenil with alcohol Chloroquine production process If they're coming and going more than likely it isn't the Plaquenil. From what I understand it is very rare for someone to have an allergic reaction to the Plaquenil and when they do that isn't how it shows up. Hopefull it's not the Plaquenil because this drug is really a very good drug for Lupus. Have a very low + ANA screen speckled, but so far neg. with mostly everything else that was last years bloodwork Doing another round in 2 weeks. I am wondering how long a malar rash presents itself. I took pic. for my rhueme. next week because it only lasted a few days.is very light. It does not hurt, only feels hot. Mar 25, 2015 I have started Plaquenil 3 weeks ago and the last week developed a rash all over sounds exactly like yours burning and itching but nothing on my face so I was doubting that it could be a lupus rash. Rhema appointment is still a month away and the rash is getting worse by the day. Hope you are doing well Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How long for plaquenil rash to go away Hydroxychloroquine Skin Support, Malar rash.long does it last? - How to stop body itching caused by chloroquine Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Allergic reaction to Plaquenil Lupus Forums at The Lupus Site. Hydroxychloroquine Oral Route Precautions - Mayo Clinic. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Mild side effects may go away within a few days or a couple of weeks. Using this drug for a long. An allergic skin rash that is caused by medication may last for weeks before the source is identified and usually resolves once the medication is stopped. The Wrap Up If you suddenly become itchy and begin to break out in hives anywhere on your body, you may be experiencing an allergic rash.