It regulates the activity of the immune system, which may be overactive in some conditions. Hydroxychloroquine can modify the underlying disease process, rather than simply treating the symptoms. Hydroxychloroquine monitoring ophthalmology Hydroxychloroquine widely used Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hi. I have been taking Plaquenil since July 9, 2006 6 weeks and I do not notice results so far. For those of you who have taken it, how long does it take to work and how will I know it's starting to work? I really appreciate your response. I have arthritis in my feet and ankles. My question is for those that have taken Plaquenil/Hydroxychloroquine. How long did it take for it to remove symptoms in your personal experience? I know I've read it can take up to 6 months but what I'm wondering is, do you just wake up one day and find it's kicked in 6 months down the road or more likely, it starts to work slowly over 6 months? Hydroxychloroquine is often taken in combination with other drugs such as methotrexate. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. It may be as long as 12 weeks before you notice the benefits. Why does plaquenil take so long to work Plaquenil Hydroxychloroquine - Side Effects, Dosage., Bone Joint Muscle - Arthritis Plaquenil - How long till it. Plaquenil for dermatomyositis muscle weaknessIndocin and plaquenilFda warning sandoz hydroxychloroquineStarting plaquenil Hydroxychloroquine is a DMARD. The brand name is Plaquenil. What does Plaquenil do? Plaquenil relieves pain and swelling and prevents damage to joints. How long does Plaquenil take to work? Plaquenil works very slowly. In 1 to 3 months you should start to feel better. You may continue to get better for up to 1 year. Lupus Medicines Hydroxychloroquine - Brigham and Women's.. How long did Plaquenil/Hydroxychloroquine take? DailyStrength. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Long term ratings 3/5. This is a reivew of how effective Plaquenil hydroxychloroquine sulfate is for Osteoarthritis and for what kind of people. The study is created by eHealthMe from 10 Plaquenil users and is updated continuously. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. Plaquenil is not deposited into fat,” he explains. “That is why it is recommended that we go by ideal body weight, or IBW—taking into account lean body mass more so than any extra fat mass in people who are overweight.” The American Association of Ophthalmology recommends using the "Devine formula" to determine ideal body weight. Mar 24, 2011 Had headaches with the plaquenil so went to the sulfar and predisone. Sulfar was a waste of time and since I had a little help from the plaquenil he switched me back to that with pain meds for the headaches and body. Recently i went back for app. and plaquenil had stopped doing anything so he added the methotrexate to it. I did not want to take it.