Please review the following URL and make sure that it is spelled correctly. Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil toxicity heart Chloroquine resistant malaria prophylaxis Plaquenil retinal screening guidelines Side effects are all GI related for the first few weeks to a month, but are no longer a problem after your body adjusts to the med. I also grew my hair back quickly & fully within a year of starting Plaquenil. It is FANTASTIC for fatigue & pain. I am sick much less often than prior to starting Plaquenil hydroxychloroquine is the generic name." Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Is anyone taking Plaquenil and if so, do you find it works for fatigue. Should I just bite the bullet and give it a whirl. I should mention that I believe many of my aches and pain is related to the fact that I am obese especially in hips/knees. I imagine this plays a part in how tired I am at times. Malaria is common in areas such as Africa, South America, and Southern Asia. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil for fatigue Fighting Lupus Fatigue and Boosting Energy, Hydroxychloroquine Plaquenil Hydroxychloroquine sulfate weight lossHydroxychloroquine and folic acidPlaquenil hemangioma dermatologyPlaquenil psoriatic arthritisPlaquenil long term use lft I have been on the Plaquenil a little over a month at the full dosage. I think I am starting to see a little less fatigue and some less muscle pain. Joint stuff is taking a little longer. Side effects have gotten better. In the first month I had some GI issues but that didn't last too long. Just having less fatigue is a huge thing. Experiences taking Plaquenil for Fatigue and Muscle Pain.. Treatment/Plaquenil -. Is lethargy and tiredness a side effect of hydroxychloroquine?. Dosage for Plaquenil. The adult dose of Plaquenil to suppress malaria is 400 mg on the same day each week. The pediatric weekly suppressive dosage is 5 mg/kg of body weight. The adult dose of Plaquenil to treat an acute attack of malaria is an initial dose of 800 mg followed by 400 mg in six to eight hours and 400 mg for two more days. During my last visit, I told him I was struggling with fatigue, so he prescribed Plaquenil hydroxychloroquine. Plaquenil is an antimalarial medication that is also commonly prescribed for a variety of chronic illnesses. I take it to help combat fatigue, and the difference it makes is pleasantly surprising. Description and Brand Names. Drug information provided by IBM Micromedex US Brand Name. Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work.