I know its a supposed small risk, but thanks to Google I've uncovered some horror stories about vision issues after just 8mo-1yr and people swearing it is actually not uncommon. I've had the worst flare of my life over late summer, I've had 3 early miscarriages in 1.5 years, I'm almost always in some type of achy state or dead tired. Potential side effects and very real risks make the medication seem ridiculously dangerous. I'm not as familiar with MCTD but what I do know is that is can be just as dangerous as SLE. Is the vision loss something that will stop if the medication is stopped? Antidote of chloroquine Chloroquine-primaquine-phosphate tablets Chloroquine phosphate toxic to bacteria Plaquenil steady state To treat malaria Plaquenil is usually given for 3 days, starting with one high dose followed by a smaller dose during the next 2 days in a row. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Use protective clothing. I wonder if what you're noticing is really the change in dose. I say this because Plaquenil has a chemical half-life of 30-60 days you can confirm this on wiki or RX info on the drug--so it takes a LONG time to get out of your system.long for you to notice changes in days. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. For this reason though, it is important that you see an ophthalmologist for an exam before starting to take an anti-malarial medication for your lupus. Your external symptoms are a sign that something very wrong is going on inside you. Why in the world would anyone choose to poison themselves? You have a choice to make between letting your disease run rampant and continue to damage your body until it can no longer fight back or using one of the few weapons you have at your disposal to slow it down. Unfortunately, you have to roll the dice and decide which risk you'd rather take. How long is plaquenil good Hydroxychloroquine Plaquenil -, Let me tell you what weaning down from Plaquenil is like. Plaquenil maculopathy dosageHydroxychloroquine urticarial vasculitisReducing inflammation without plaquenilBuy chloroquine online ukPlaquenil myasthenia gravis The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Taking Plaquenil for Rheumatoid Arthritis. Treating Lupus with Anti-Malarial Drugs Johns Hopkins.. How long taking Plaquenil before side effects DailyStrength. I take Plaquenil for Lupus and it takes 4 to 6 months. For me, it always seems to take 6 months for me to feel the full effect and a marked improvement in my fatigue & joint pain. Hang in there! Plaquenil has been a life-saving drug for me, quite literally. I was a mess in 2004-2005 and then a dr put me on Plaquenil, and in 3 weeks most of my symptoms had disappeared. I'm back on it and waiting the 3-4 months it takes to work at least that's how long it took the first time. I have a great opthamologist who has assured me he will catch retinal damage before I will ever notice a change in my vision, so as far as I'm concerned, I want to stay on Plaquenil until I'm forced off it.