Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Plaquenil cdc side effects Plaquenil weight Is hydroxychloroquine immunosuppressant The rheu. has prescribed methotrexate, folic acid and Plaquenil. In doing my research I've read that metho and Plaq. are contraindicated. I don't want to get on the wrong foot and start questioning my doctor's advice, but I'm a bit concerned. Does anyone know if hydroxychloroquine and methotrexate can cause weight loss day, been taking for over a year now but although it helps with some of the pain. I have to have steroid. I was diagnosed with RA in march and have been on increasing dose of methotrexate. Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Thanks Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Can i take plaquenil and methotrexate together Which would you pick and why? - Plaquenil or Methotrexate, Does anyone take methotrexate and hydroxychloroquine. Hydroxychloroquine sulfate plaquenil side effectsCan plaquenil cause hives OBJECTIVE To examine the bioavailability of methotrexate MTX in the presence of hydroxychloroquine HCQ, and vice versa, to determine a possible pharmacokinetic explanation for the observation that combination treatment of rheumatoid arthritis with MTX and HCQ has been shown, clinically, to be more potent than MTX used alone. Combination therapy with methotrexate and.. Does anyone take methotrexate and hydroxychloroquine. - NRAS. Rheumatoid Arthritis Treatment Options Johns Hopkins.. Methotrexate is the most commonly prescribed DMARD, but it does come with the chance of side-effects. I never had any side-effects of dire consequence, but many on this forum have. Methotrexate may take longer to become effective, but USUALLY, it will take effective within the time frame you're looking at. Does it matter if you take 400 mg plaquenil hydroxychloroquine at once VS 200 in the morning and 200 in the afternoon? Is it normal to take plaquenil hydroxychloroquine for arthritis? How long does it take for plaquenil hydroxychloroquine to work with rashes? Is it possible for me to take tumeric complex if I take plaquenil. Can I still take vitamin supplements while on methotrexate? Q I take plaquenil and methotrexate for my rheumatoid arthritis, and folic acid. My rheumatology clinic has suggested not taking vitamin supplements as it's not known if they'll react with methotrexate and stop it working.