Chloroquine ototoxicity

Discussion in 'Canada Pharmacy Online' started by Privodchik, 29-Feb-2020.

  1. ribachok New Member

    Chloroquine ototoxicity

    Additionally, another exception occurred while executing the custom error page for the first exception. Ototoxicity is, quite simply, ear poisoning (oto = ear, toxicity = poisoning), which results from exposure to drugs or chemicals that damage the inner ear or the vestibulo-cochlear nerve (the nerve sending balance and hearing information from the inner ear to the brain).

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    There are some reports about chloroquine-induced ototoxicity 7-9. Severe chloroquine-induced cochleovestibular toxicity was reported in a pregnant woman. Absence of inner and outer hair cells of the cochlea was also detected in a child whose mother took chloroquine during her pregnancy. Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. The ototoxic effects can be minimized by carefully monitoring blood levels. Quinine • chloroquine phosphate Aralen • quinacrine hydrochloride Atabrine • quinine sulfate Quinam The ototoxic effects are very similar to those of aspirin. Mucosal Protectant • misoprostol Cytotec Narcotic Analgesics • hydrocodone Lorcet, Vicodin

    The parts of the brain that receive hearing and balance information from the inner ear can also be affected by poison, but this is not technically considered ototoxicity and won’t be covered in this information sheet. Because the inner ear is involved in both hearing and balance, ototoxicity can result in disturbances of either or both of these senses.

    Chloroquine ototoxicity

    Why You Should Care About Ototoxic Medications The MED-EL Blog, Chloroquine and Hydroxychloroquine Toxicity Practice.

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  6. Ototoxicity, drugs, chemicals, mobile phones and deafness MK Taneja 1, Himanshu Varshney 2, Vivek Taneja 1, Jitendra Varshney 3 1 Senior ENT and Head Neck Surgeon, Indian Institute of Ear Diseases, New Delhi, India 2 ENT Surgeon; Sri Sai Hospital, Moradabad, Uttar Pradesh, India 3 Sri Sai Hospital, Moradabad, Uttar Pradesh, India

    • Ototoxicity, drugs, chemicals, mobile phones and deafness..
    • Ototoxic Medications - hlaa-.
    • Chloroquine - Wikipedia.

    Most important agents to cause irreversible ototoxicity are Aminoglycosides and Cisplatin. FACTORS INFLUENCING OTOTOXOCITY Drug concentration in inner ear Dose, Absorption, Clearance from body, Selectivity to ear Intolerance Renal and hepatic disease Placental transport Chloroquine, Streptomycin can lead to ototoxicity in fetus Genetic. Ototoxicity have been found when these medications are taken orally in high doses by people with chronic kidney disease. Quinine • chloroquine phosphate Aralen •quinacrine hydrochloride Atabrine •quinine sulfate Quinam The ototoxic effects are very similar to those of aspirin. Mucosal Protectant • misoprostol Cytotec Narcotic. Chloroquine is related chemically to quinine and, because of this similarity, has been suspected of being an ototoxic drug. 1 It is currently being used for the treatment of malaria, amebiasis, rheumatoid

  7. z80 XenForo Moderator

    500 mg chloroquine phosphate (300 mg base) orally on the same day each week Comments: -If possible, suppressive therapy should start 2 weeks prior to exposure; if unable to start 2 weeks before exposure, an initial loading dose of 1 g chloroquine phosphate (600 mg base) may be taken orally in 2 divided doses, 6 hours apart. Chloroquin Chloroquine Dosage Guide with Precautions - Chloroquine and Hydroxychloroquine Toxicity Practice.
  8. Linkmaker New Member

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  9. IT-Security New Member

    Plaquenil Withdrawal – Life As An Anomaly Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me.

    Chloroquine and hydroxychloroquine – Knowledge for medical.