While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Drug interactions are reported among people who take Hydroxychloroquine sulfate and Sulfasalazine together. Chloroquine phosphate tablets 250 mg dosage Lupus medications chloroquine How to tell if plaquenil is causing blindness Because sulfasalazine can affect your liver, you should avoid heavy alcohol use while taking it. It is not known precisely what level of drinking is safe when on sulfasalazine. However there is general agreement that 1 to 2 standard drinks taken once or twice a week is unlikely to cause a problem. Sulphasalasine was helpful in my case but took 12 weeks to kick in. After a while it wasn't as effective and I too was prescribed methotrexate alongside. The side effects of the methotrexate for me were horrendous chronic chest infections and I'm now asthmatic as a result. I refuse to take it now even if its my passport to biologic treatment. Drug interactions are reported among people who take Sulfasalazine and Plaquenil together. This study is created by eHealthMe based on reports of 7,132 people who take Sulfasalazine and Plaquenil from Food and Drug Administration FDA, and is updated regularly. eHealthMe has been monitoring drugs since 2008. E Health Me's original studies are referenced on 600 peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. This study is created by e Health Me based on reports of 1,913 people who take Hydroxychloroquine sulfate and Sulfasalazine from Food and Drug Administration (FDA), and is updated regularly. Can sulfasalazine and plaquenil be taken together Sulfasalazine Side-effects, uses, time to work, Combination hydroxychloroquine and sulfasalazine - do. Effects of hydroxychloroquine on tasteHydroxychloroquine mideCan someone with glucoma take plaquenilHydroxychloroquine sulphate bp 200mg Interaction between Plaquenil and Sulfasalazine There is no known interaction between Plaquenil and Sulfasalazine in our records. However, an interaction may still exist. Always consult your doctor before taking these medications together. Do not stop taking the medications without a physician's advice. Compare Plaquenil vs Sulfasalazine - Comprehensive.. Sulfasalazine and Plaquenil drug interactions - eHealthMe. Methotrexate, Plaquenil or Sulfasalazine Azulfidine.. Early, aggressive disease management is critical for halting disease progression and joint destruction in patients with rheumatoid arthritis. Combination therapy with at least two disease-modifying antirheumatic drugs, such as methotrexate MTX, sulfasalazine, or hydroxychloroquine, is often more effective than monotherapy in reducing disease activity. My recommendation is not to even be on the drug. It is helpful but don't think you can't get plaquenil toxicity. You can. And it's bad. And I had an ophthalmologist tell me for 15 years that my symptoms had nothing to do with plaquenil and to stay on it because he never did a real plaqueninl examination on me. I started taking sulfasalazine SZS with Plaquenil 2 months ago for RA. Immediately felt dizzy, confused, nosebleed and depression and also severe vision changes. Bi-Weekly blood draws were a total painful waste of time. Then began a very intense ringing in my ears. Discontinued Plaquenil twice a day, and dropped the SZS from 4 per day to 3.