Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Does plaquenil show up on a drug test Plaquenil and lupus rash When taking plaquenil which tests should periodically be taken Plaquenil for crest syndrome Plaquenil pigmentation. Close. Positive then negative ANA test. So I know ANA tests are weird and can be positive for no reason, but mine has been positive for almost 5 years now with an increasing titer. My doctors have been looking into the possibility I have an autoimmune disease after I became sick two years ago and still haven’t. I’ve had pleuritis 3 weeks ago in which I am currently taking prednisone 10mg for 2 weeks and then 5mg for two weeks. I have been taking plaquenil and meloxicam for a few months now. I have had the million dollar work up for lab work, all of which came back negative each time. 2 weeks ago, I saw my Rheumy, I was having a really bad flare. If you go to the Mayo Clinic Lupus website it will give the info on there. It can also take years for an ANA to turn positive or sometimes when you blood is drawn it is negative at that time, but it does not mean it is always negative. It took me year and years of being ill to have a positive ANA and other blood work. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Taking plaquenil with negative ana Positive ANA Negative anti-dsdna at titer? Lupus., ANA negative Lupus - @LadyLupie - Lupus - 20171030 - Inspire Plaquenil mefioquineHydroxychloroquine blood monitoringCan you take berberine with plaquenilPlaquenil associated hyperpigmentation I had one positive ANA and then negative. My rehumy put me on plaquenil. It helped some. Later he told me I also have fibromyalgia and started lyrica which has tremendously helped. My ANA stays negative and he says that because I don't have severe disease and due to being on the plaquenil that my ANA is staying negative. Can Plaquenil cause a false negative ANA - Lupus - MedHelp. Lupus with negative blood work DailyStrength. A negative ANA? DailyStrength. No fetal abnormalities are known to have occurred from taking hydroxychloroquine, and physicians at several major universities have used anti-malarial drugs for years to treat pregnant women with lupus without negative side effects on the fetus. What should I keep in mind when taking anti-malarial drugs? Doctors give trusted answers on uses, effects, side-effects, and cautions Dr. Friedlander on positive ana on plaquenil One of the things that's frustrating about these antibody tests looking for different connective tissue diseases is that they are difficult to do and are fraught with pitfalls. I know this is an old post but Jennifer I had a question. I have been taking plaquenil for 7 years. I take 200mg per day. I have sjogrens and cutaneous lupus. MY ANA is homogeneous,SSA 4.6, SSB normal ESR 31. All other lab negative. Recently I had shingles and was given prednisone which then caused an outbreak of HP.