Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Plaquenil and sunburn 30-2 plaquenil Iron salts may be harmful and result in iron overload if given alone to patients with anaemias other than those due to iron deficiency. Sickle-cell anaemia Sickle-cell disease is caused by a structural abnormality of haemoglobin resulting in deformed, less flexible red blood cells. People with sickle cell disease SCD start to have signs of the disease during the first year of life, usually around 5 months of age. Symptoms and complications of SCD are different for each person and can range from mild to severe. If you manage your condition, you can live a full, active life with sickle cell disease. Follow tips for a healthy lifestyle that can help reduce your chances of pain. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Would chloroquine in a sickle cell patient beh harfmul The Traveler with Sickle Cell Disease, Complications and Treatments of Sickle Cell Disease CDC Chloroquine primaquine combination Emergency Guide When to See the Doctor. It is very important that every person or family with a child with sickle cell disease has a plan for how to get help immediately, at any hour, if there’s a problem. Fact Sheet Sickle Cell Disease and College. Nine steps to living well with sickle cell disease in college. Fact Sheets on Sickle Cell Disease CDC. Tips for Managing & Living With Sickle Cell Disease. Sickle cell disease and malaria morbidity a tale with two.. Mar 16, 2017 Current therapy for patients with sickle cell disease relies on red blood cell transfusions. However, there are few guidelines regarding the optimal red cell unit to be delivered to these patients. An important factor that is currently not addressed in the practice of blood cell transfusions in sickle cell disease is the storage age of the red. Lifestyle changes will not cure sickle cell disease. However, they may reduce the number and severity of sickle cell crises. General Guidelines for Managing Sickle Cell Disease. Eat a balanced diet, including folic acid supplementation; Drink plenty of water; Avoid excessive exercise; Get sufficient rest; Rest in bed during acute sickle cell crisis Several cases of hypopigmentation of the skin have been reported. Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy.