Chloroquine prophylactic therapy

Discussion in 'Cheap And Quality Drugs' started by polad, 24-Feb-2020.

  1. Janosch Well-Known Member

    Chloroquine prophylactic therapy


    I don't know that we've seen the formal research yet on treatment of symptomatic patients, but given the mode of action and supposed efficacy on the outcomes of more seriously ill patients that China is claiming, wouldn't that possibly also work as a prophylactic agent? Whether or not that is a good idea is a public health policy question - you would push the virus to mutate a lot faster like Malaria has if used as prophylaxis vs if you saved it only for already isolated sick patients - but it might be very effective with known contacts in early outbreaks to improve early quarantine effect of those exposed.

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    CHLOROQUINE PHOSPHATE, USP DESCRIPTION ARALEN, chloroquine phosphate, USP, is a 4-aminoquinoline compound for oral administration. It is a white, odorless, bitter tasting, crystalline substance, freely soluble in water. ARALEN is an antimalarial and amebicidal drug. Adult 100 mg chloroquine base once daily always combined with proguanil Travellers should start prophylaxis 24 hours before departure, continue throughout the stay and for at least 4 weeks after return. In areas where resistance to chloroquine is high, chloroquine must be replaced by another effective antimalarial suitable for prophylactic use. Education and information regarding choosing a drug to prevent malaria, including a list of all available drugs and reasons for taking or not taking a certain drug.

    Anyone heard anything about this, or have speculation on if that would be effective at the more tolerable malaria prophylaxis dose (or the accelerated loading dose maybe). And, it's possible to OD on Chloroquine if you don't follow the directions, or have un-diagnosed mild or moderate G6PD deficiency or certain other conditions, which has to be considered, and the drug clears from your system very slowly.

    Chloroquine prophylactic therapy

    Chloroquine - Wikipedia, CHLOROQUINE sulfate or phosphate oral - Essential drugs

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  6. Severe acute respiratory syndrome SARS is caused by a newly discovered coronavirus SARS-CoV. No effective prophylactic or post-exposure therapy is currently available. We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the.

    • Chloroquine is a potent inhibitor of SARS coronavirus infection and..
    • CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria.
    • Chloroquine - LiverTox - NCBI Bookshelf.

    Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. Before using chloroquine for prophylaxis, it should be ascertained whether chloroquine is appropriate for use in the region to be visited by the traveler. Chloroquine should not be used for treatment of P. falciparum infections acquired in areas of chloroquine resistance or malaria occurring in patients where chloroquine prophylaxis has failed. Chloroquine appears to be more retinotoxic than hydroxychloroquine. Screening recommendations for chloroquine All patients planning to be on long-term treatment should receive a baseline examination including fundus photography and spectral domain optical coherence tomography within 6-12 months of treatment initiation;

     
  7. empiteBed Guest

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  8. Pimply Moderator

    Chloroquine has long been used in the treatment or prevention of malaria from Plasmodium vivax, P. malariae, excluding the malaria parasite Plasmodium falciparum, for it started to develop widespread resistance to it. Drugs & Medications - Chloroquine Aralen - Side Effects, Dosage, Interactions. Chloroquine Uses, Side Effects, Dosage & Interactions
     
  9. nedurak New Member

    Colchicine/hydroxychloroquine SpringerLink Lonesky TA, Kreuter JD, Wortmann RL, Rhodes CH. Hydroxychloroquine and colchicine induced myopathy. The Journal of Rheumatology 36 2617-2618, No. 11, Nov 2009 - USA

    Mechanism of the anti-inflammatory effect of colchicine in.
     
  10. Glotych Well-Known Member

    Taking Plaquenil for Various Conditions and Treatment Tips This eMedTV selection features Plaquenil dosing guidelines for malaria, lupus, and rheumatoid arthritis. Also included in this segment is information on how to take the medication most effectively and what to do if you have any questions.

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