This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil dr mercola Plaquenil and valium Find patient medical information for Chloroquine Phosphate Bulk on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Quinine and chloroquine poisoning are characterized by severe cardiovascular toxicity resulting from sodium and potassium channel blockade, leading to hypotension, shock, arrhythmias and cardiac arrest. Quinine poisoning can cause irreversible visual loss. Severity of symptoms is closely related to the ingested dose and plasma concentration. Descriptions of chloroquine intoxication in the literature, commonly characterized as toxic psychosis, are similar to those associated with other quinolines and typically feature insomnia 13, 14, mania 15, 16, paranoia and persecutory delusions 17, and auditory and visual hallucinations 18. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine and depression The antimalarial drugs quinine, chloroquine and mefloquine., Quinine and chloroquine - ScienceDirect Plaquenil drugBenefits of plaquenil for rheumatoid arthritisDoes hydroxychloroquine cause cancer Jul 30, 2019 Frequency not reported Neuropsychiatric changes, psychosis, mania, delirium, anxiety, agitation, insomnia, confusion, personality changes, depression, other psychiatric and neurologic disturbances, development of extrapyramidal rigidity, paranoia, hallucinations. Mania has been reported in a patient taking chloroquine for malarial prophylaxis. Chloroquine Side Effects Common, Severe, Long Term -. Prolonged neuropsychiatric effects following management of.. Antimalaria pills linked to depression what travellers.. The excretion of Chloroquine and the major metabolite, desethylChloroquine, in breast milk wasinvestigated in eleven lactating mothers following a single oral dose of Chloroquine 600 mg base. The maximum daily dose of the drug that the infant can receive from breastfeeding was about 0.7% of the maternal start dose of the drug in malaria chemotherapy. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. A severe eye problem has happened with chloroquine. This may lead to lasting eyesight problems. The risk may be higher if you have some types of eye or kidney problems. The risk may also be higher with some doses of chloroquine, if you use chloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen.