It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine undifferentiated connective tissue disease Plaquenil and puffy face Nov 02, 2010 It takes around 5.5 half lives for a drug to be completely eliminated from your body meaning that you may need to wait for around 176 days. Further Information Hydroxychloroquine Drug Information The usual starting dose of Plaquenil is 200 mg twice a day or 400 mg once a day, administered orally, in people weighing 80 kg or more. The usual dosage works for most people who take Plaquenil, but it is possible to increase or decrease the dose based on individual needs. It's important to watch for possible side effects and toxicity. Jan 10, 2018 According to the American Addiction Center, hydrocodone can be detected in saliva for 12 to 36 hours after the last dose is taken. urine for up to four days after the last dose is taken. hair for up to 90 days after the last dose is taken. Today, it is used to treat rheumatoid arthritis, some symptoms of lupus, childhood arthritis (or juvenile idiopathic arthritis) and other autoimmune diseases. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. How long will plaquenil stay in your system Lupus Medicines Hydroxychloroquine - Brigham and Women's., Taking Plaquenil for Rheumatoid Arthritis Drug quinine and chloroquineHow long for chloroquine to workPlaquenil moaHypnozoite chloroquine resistanceHydroxychloroquine overdose symptoms Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Plaquenil -. How Long Does Hydrocodone Stay in Your System?. Hydroxychloroquine Plaquenil. First, my mother and sister took plaquenil for lupus with good effect, so I am not just disliking it for no good reason. I also suffer from disabling bipolar disorder. For 25 years, I have gotten hypomanic during spring. Very happy, never depressed. When I started taking Plaquenil, I got a bit depressed but that's not a big deal. May 05, 2016 Plaquenil seems to be a good baseline drug to start when first diagnosed with inflammatory connective tissue disease and one that many people will probably stay on for continued disease management. Stop guessing how long marijuana, cocaine and most other drugs actually stay in your system. Marijuana is up to 60 days!