Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Plaquenil and vascular system Hydroxychloroquine sulphate Diagnosis code for plaquenil therapy Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in Hydroxychloroquine side effects. Get emergency medical help if you have signs of an allergic reaction to hydroxychloroquine hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Hydroxychloroquine side effects medbullets Hydroxychloroquine Sulfate Bulk Uses, Side Effects., PATIENT FACT SHEET Hydroxychloroquine Plaquenil Side effects stopping plaquenil The only side effect taking the drug for me was severe burning mouth syndrome, ringing in the ears and an overall dryness. I am concerned with the drug affecting my vision. I stopped taking the drug because of the cost of am eye exam and office visits and lack of insurance. I am not in a flair. Plaquenil Drug and Medication User Reviews on RxList. Hydroxychloroquine Uses, Dosage & Side Effects -. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Generic Plaquenil. HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus erythematosus. It is also used to treat malaria. The lowest GoodRx price for the most common version of hydroxychloroquine is around $18.60, 90% off the average retail price of $196.17. Call your doctor right away if you notice any of these side effects Wheezing or trouble breathing. Severe or bloody diarrhea. Blurred vision or eye problems. Skin rash or itching. Unexplained fever, unusual bleeding or bruising. If you notice these less serious side effects, talk with your doctor Headache. Nausea or upset stomach. Diarrhea. Appetite loss For the Consumer. Continuing ringing or buzzing or other unexplained noise in the ears. feeling of constant movement of self or surroundings. irritability. nausea. nervousness. nightmares. sensation of spinning. shakiness and unsteady walk. uncontrolled eye movements. unsteadiness, trembling, or.