Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Whhat kind of damage does plaquenil cause to the eye Hydroxychloroquine organ damage Chloroquine in first trimester pregnancy Mferg plaquenil Shin pain is often referred to as shin splints, but not all shin pain is necessarily caused by shin splints. The pain may come from irritation of the muscles and the tissues that connect the muscles to bone, from a stress reaction/fracture or from increased pressure around the muscles in the lower leg. Lupus and leg pain Bret_Michelle. I was diagnosed with lupus in Aug 2009 and put on plaquenil. I have seen a little difference in the dry mouth but the dry eyes are still here, which I have been store brand eye drops for. I have been having this leg pain for about a year or so now and it feels like my legs could just break. The term "shin splints" refers to pain along the shin bone tibia — the large bone in the front of your lower leg. Shin splints are common in runners, dancers and military recruits. Medically known as medial tibial stress syndrome, shin splints often occur in athletes who have recently intensified or changed their training routines. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Shin pain plaquenil HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical., Lupus and leg pain - Autoimmune Disorders - MedHelp Plaquenil dosage for ra Plaquenil or hydroxychloroquine has been known to cause a darkened discoloration of skin and/or mucous membranes. This is considered an adverse reaction and should be discussed with your prescriber. It is important to evaluate this color change to make sure there is nothing else wrong. Skin Discoloration and Plaquenil - Arthritis Information. Shin splints - Symptoms and causes - Mayo Clinic. Pains in Your Shin That Might Not Be Shin Splints ACTIVE. Shin pain is a common complaint, especially in runners. Here we explain the many causes of pain on the inside of the shin, as well as injuries causing pain on the outside of the shin. Shin splints is a common term used to describe shin pain. Hydroxychloroquine is the generic form of Plaquenil but the side effects are the same. My thigh muscles are so sore I can hardly walk, sit or stand. Stairs are a TRUE challenge. I have to struggle up and down taking only one step at a time using only one leg at a time. The term shin splints describes pain felt along the inner edge of your shin bone. This pain concentrates in the lower leg between the knee and ankle. Shin splints often occur in people engaging in.