Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Reducing inflammation without plaquenil Plaquenil and imuran heat and sun side effects Jun 15, 2017 Treatment depends on how much of the scalp is affected and how quickly the condition progresses. A high or moderate potency steroid cream is often effective in treating lichen planopilaris. If this is not effective, steroid injections into skin lesions, or systemic corticosteroids taken by mouth may be considered. You are supposed to have a blood test every month to check on your liver and kidneys as long term use can affect them. I was told also to keep an eye out for 'floaters' in my eyes, as Plaquenil can cause macular damage to your retinas. I'm only on a low dose, but now have a black line floating over my eye. In general patients with lichen planopilaris may have itching of the scalp and some may have increased hair shedding. They may also have burning, pain and tenderness in the scalp. Some patients note that the scalp is tender when the hairs are moved. There may be redness in the scalp and some scale. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. How can plaquenil scarring alopecia Central centrifugal cicatricial alopecia DermNet NZ, Plaquenil Hydroxychloroquine anyone? - Alopecia World Plaquenil eye exam frequency Lichen planopilaris is the most common cause of cicatricial alopecia and accounts for at least 10% of cases. 6 Lichen planopilaris is a clinical variant of lichen planus; both conditions can occur simultaneously. Frontal fibrosing alopecia is a variant of lichen planopilaris. Primary cicatricial alopecia diagnosis and treatment. Lichen Planopilaris — Canadian Hair Loss Foundation. Plaquenil Side Effects Common, Severe, Long Term -. Re Plaquenil and hairloss. Hi, there. Plaquenil will eventually help your hair loss, but that will be a very slow process over a long period of time since plaquenil builds up in your body pretty slowly. And you should keep your head a scalp protected from the sun as VeeJ said. Most forms of scarring alopecia first occur as small patches of hair loss that may expand with time. In some cases the hair loss is gradual, without noticeable symptoms, and may go unnoticed for a long time. In other instances, the hair loss is associated with severe itching, burning, and pain. Hydroxychloroquine Plaquenil is a slow acting drug. It can take up to 8 weeks or more before the medication really starts to have an effect and actually help an individual using the drug. Because hydroxychloroquine is so delayed in its onset, I usually give it 4-6 months before really deciding if it is working. and sometimes even longer.