Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Can plaquenil treat psoriasis Plaquenil cream Can plaquenil cause joint pain Is chloroquine a quinoline Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Aug 22, 2011 Plaquenil has never raised my liver enzymes and I have been on it for six years. The only time my ALT and AST were elevated when I was taking too much iron supplements for my anemia. Once I stopped those, the enzymes went back to normal. Liz D. I have recently started taking plaquenil foe RA. My doctor called and said their was a slight change in my liver numbers. He said it is nothing to worry about. I was wondering does plaquenil affect your liver? If any of you experienced this please let me know. Thank-you, JK Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Liver enzymes plaquenil Ways to Lower Liver Enzymes - wikiHow, Plaquenil and elevated liver enzymes? - Sjogren's World Sickle cell disease plaquenil Other less common causes of abnormal liver enzymes include Crohn’s disease, ulcerative colitis, autoimmune hepatitis, celiac disease, or viral infections other than hepatitis viruses. What was the cause of my elevated liver enzyme levels? Since these test results were very much out of the ordinary for me, my doctor wanted to retest in a month. Why Are My Liver Enzyme Levels Elevated.. Does plaquenil elevate your liver enzymes? ProHealth Fibromyalgia, ME.. Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs.. Apr 10, 2007 I have recently started taking plaquenil foe RA. My doctor called and said their was a slight change in my liver numbers. He said it is nothing to worry about. I was wondering does plaquenil affect your liver? If any of you experienced this please let me know. Thank-you, JK Elevated liver enzymes are a common problem in some patients being treated with hydroxychloroquine, such as patients with lupus. However, as a general rule, hydroxychloroquine is not associated with an elevation in liver enzymes when used to treat autoimmune and rheumatologic diseases. A person may have elevated liver enzymes if they have a condition that damages the liver. Learn about the possible causes of elevated liver enzymes and their symptoms and treatment options here.