I've been taking it for about 6 months now, and I can't tell that it's done a thing. I think I may be overmedicated and was thinking about dropping the plaquenil if there was no benefit to it. Thanks, Elcamino Hi Elcamino, I have been taking Plaquenil (400 mg per day) for about 2 years now due to lupus flare. History of chloroquine Chloroquine maculopathy emedicine Can plaquenil change ana Hydroxychloroquine sulfate 200 mg film coated tablets How long does it take for plaquenil to work - Kim.luck. I'm crossing my fingers with you. Hopefully you can get back to Plaquenil and it will work for you. I had almost no side effects except for an minor upset stomach if I didn't eat when taking the pill. I think we're lucky there are drugs to Damage to the retina, the light sensitive portion of the inner eye, can occur with long-term use of Plaquenil or chloroquine Aralen. With Plaquenil, however, the most commonly prescribed anti-malarial, this sort of damage occurs only in 1 out of 5,000 people who take the drug for five years or more. User Reviews for Plaquenil to treat Rheumatoid Arthritis. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Actually I started on 200 mg per day and about 2 months before tapering off pred, he upped me to 400 mg per day of plaquenil to give it plenty of time to kick in. When i first started it, I was also started on prednisone to get my inflammation under control. How long does plaquenil take to work for ra Plaquenil for fatigue and pain DailyStrength, Treating Lupus with Anti-Malarial Drugs Johns Hopkins. Does plaquenil help with lupus fatiguePlaquenil 200 mg tablet adalahHydroxychloroquine 200 mg does it make u gain weightChloroquine malarone Hi Guys, I haven't been here for a while - just checked in and found this question on Plaquenil - for me it took approx nine weeks to begin to work - I'm only taking 200mg per day so far - it seemed to stop working a few weeks later - most days are pretty good I s'pose but I drop nearly every afternoon. Immune & Autoimmune - Lupus Plaquenil - Can It Work Quickly?. Plaquenil User Reviews for Rheumatoid Arthritis at. PLAQUENIL" Rheumatoid Arthritis Community - Support Group. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Nov 14, 2006 Someone else told me that plaquenil could take up to a year to work. Others have told me that it only took a few months for them to feel the effects. Everyone is different. I can tell you that plaquenil is the safest of all of the DMARDs. If you're going to stay on a DMARD for a long time, plaquenil is the one to be on. Best of luck on the. Plaquenil is a DMARD which has been prescribed for years to treat rheumatoid arthritis, lupus, juvenile rheumatoid arthritis, and other autoimmune diseases. When the first biologic DMARD received FDA-approval in 1998, and as other biologics followed in subsequent years, it appeared as though Plaquenil would become less prescribed.