13 mg/kg (10 mg/kg base), not to exceed 800 mg (620 mg base) followed by 6.5 mg/kg (5 mg/kg base), not to exceed 400 mg (310 mg base), at 6 hours, 24 hours and 48 hours after the initial dose. PLAQUENIL film-coated tablets cannot be divided, therefore they should not be used to treat patients who weigh less than 31 kg. Does plaquenil help Process related impurities in chloroquine and hydroxychloroquine On Plaquenil, LDN and Methotrexate and the pain doesn't stop. My poor knuckles hurt SO much. Any time I use my hands they swell up and it's like stabbing pain. My. Often they start with the old stand-by of MTX as Plaquenil is not aggressive enough for some of the joint conditions they see and that is their primary concern. Although the leading research on LDN in the country has been done by UCSF, they have backed off its use except for MS. There has been about a 10% SE rate with LDN similar to that of full dose. Hello, I am new to this site and to LDN. This is my 22nd day. When I started this my doctor recommended that I stay on Plaquenil. Dx SLE, Sjogren's & Fibromyalgia. I would appreciate if I could 400 mg to 600 mg (310 to 465 mg base) daily, administered as a single daily dose or in two divided doses. For radical cure of The recommended adult dosage is 200 to 400 mg (155 to 310 mg base) daily, administered as a single daily dose or in two divided doses. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Ldn and plaquenil Plaquenil Dosage Guide -, Low Dose Naltrexone - Complementary Therapy - Sjogren's. Plaquenil and brain dizzinessPlaquenil and biaxin for lyme diseaseBenefits of hydroxychloroquineChloroquine and tonic waterPlaquenil hydrochloroquine I am looking to hear from anyone who has tried LDN low dose naltrexone for Sjogren's with success or failure. I am mostly interested in hearing about its impact on symptoms of dryness and glandular inflammation. I have seen a number of LDN related posts but very little follow up stories. Low dose naltrexone stories for Sjogren's?. LDN and Plaquenil Low Dose Naltrexone Forum. Using Low Dose Naltrexone for Lichen Planopilaris LPP.. Does anyone take plaquenil and LDN? I recently flared after taking 1 plaquenil a week for a few years. Now taking 2 a day again, 3 weeks in and not feeling better yet. Extreme cognitive dysfunction and I can't work. My dr prescribed the low dose naltrexone to me but I'm afraid to take it. I recently started Low Dose Naltrexone for pain and I had an opportunity to see it work positively for a Lupus flare. I was then interviewed on the radio. Nov 21, 2017 LDN is not an opiate and is not a controlled substance. It is an opiate blocker and is used in regular dosages 50mg to help patients stop abusing alcohol and opiates. However, at lower dosages it has been found to have anti-inflammatory effects, especially in the brain and around nerves.