Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Does plaquenil lower your immune system Plaquenil cause hair loss Plaquenil patient assistance application While side effects of corticosteroids are usually to blame, there is also the possibility of ocular damage associated with long-term use of the antimalarial drugs hydroxychloroquine brand name Plaquenil® and chloroquine. Improved vision screening tests and updated dosing guidelines are key to avoiding such complications. She claimed my husband's eye condition was due to his age, and not Hydroxychloroquine, of which retinal damage is a well-known side effect. My husband has continued to get more flashes and floaters. His right eye is pretty useless now. According to Drugs.com, Plaquenil given for a long term can cause retinal disorders after a few months or years of daily use--especially if the dose exceeds 400mg per day. The risk of retinal damage increases at doses of 600mg to 700mg. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Plaquenil retinal damage Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis, Hydroxychloroquine causing retinal damage My husband. - NRAS Plaquenil evaluation eyesHydroxychloroquine sulfate melasma If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. Plaquenil Side Effects on Your Eyes and Vision. Long-Term Side Effects of Plaquenil for Rheumatoid.. Hydroxychloroquine Plaquenil Toxicity and.. Anyone on Plaquenil is almost always ordered to have annual visits with a Retinologist for those tests and have a baseline test at beginning of Plaquenil to determine if damage occurs. Did a retina specialist say there was retina "thinning"? Retinal toxicity of Plaquenil may manifest itself with subtle disturbances of the retinal pigment epithelium which may eventually lead to complete destruction of the macula in the form of bull’s-eye maculopathy. Several risk factors may increase the likelihood of retinal toxicity from Plaquenil such as. Hydroxychloroquine Plaquenil; HCQ has been an important and effective drug for the treatment of lupus erythematosus and related autoimmune and inflammatory diseases for half a century, although its potential to cause retinal damage continues to raise concern among rheumatologists and ophthalmologists.