What is the half life of plaquenil

Discussion in 'Pharmacy Northwest Canada' started by Alen5, 17-Mar-2020.

  1. aamilskaya XenForo Moderator

    What is the half life of plaquenil


    Hi Dr V, I am at a crossroad of considering to go back on Plaquenil . A year ago I proposed to go off Plaquenil after being on it for 22 years.

    Chloroquine maculopathy oct Does hydroxychloroquine interact with levothryoxine High risk drug use icd 10 plaquenil

    Plaquenil pla´kwĕ-nil trademark for a preparation of hydroxychloroquine, an antiinflammatory and antiprotozoal agent used for treatment of malaria, lupus erythematosus, rheumatoid arthritis, and giardiasis. Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported. This article focuses upon hydroxychloroquine retinopathy. Disease Hydroxychloroquine HCQ, sold under the brand name Plaquenil among others, is a medication used for the prevention and treatment of certain types of malaria. Specifically it is used for chloroquine-sensitive malaria. Other uses include treatment of rheumatoid arthritis, lupus, and porphyria cutanea tarda. It is taken by mouth.

    If I had joint or muscle aches, I took care of it by resting, Aleve and ice. At my recent eye exam the doctor mentioned I had reached the plaquenil toxicity level and that my retina cells could die (which do not regenerate! My proposal was based on the fact that I had not had any major inflamation that completely shut me down or keep me from being active.

    What is the half life of plaquenil

    Plaquenil Hydroxychloroquine Sulfate, Hydroxychloroquine toxicity - EyeWiki

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  7. An analog of chloroquine – hydroxychloroquine – has a long half-life 32–56 days in blood and a large volume of distribution 580–815 L/kg. The therapeutic, toxic and lethal ranges are usually considered to be 0.03 to 15 mg/l, 3.0 to 26 mg/l and 20 to 104 mg/l, respectively.

    • Chloroquine - Wikipedia.
    • Hydroxychloroquine - Wikipedia.
    • Let me tell you what weaning down from Plaquenil is like..

    Yes. The half life is 1-2 months. The half life is the time it takes for half of the drug to be eliminated from the body. So even after 2 months, it is still present. This means it continues to work during that time. Plaquenil is very effective for the symptoms of achiness and fatigue. However, there might be a price to pay in terms of retinal toxicity especially after taking it for as long as you have. Given that the alopecia had developed while you were on the plaquenil, it's not clear that going back on it will help that symptom much. I had life threatening issues that sent me to the ER - twice - and each time, Plaquenil brought me back from the brink and set me on an even keel. Please be patient and try to tough out the GI issues and give it 2-3 months. This drug can save your life if you give it a chance.

     
  8. seo07 Well-Known Member

    Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Methotrexate vs. Plaquenil - Autoimmune diseases - Inspire Plaquenil Uses, Dosage & Side Effects - Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  9. aRu User

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    Hydroxychloroquine Oral Route Description and Brand.
     
  10. 095 Moderator

    Chloroquine use in transfection. - Tissue and Cell Culture Chloroquine use in transfection. - Oct/14/2011 Hello all, I wanted to transfect the HEk cells with lentiviral vector. Before addition of the transfection complex I forgot to treat the cells with chloroquine. what is the purpose of chloroquine in transfection? Can anyone please tell me whether the transfection has taken place, as i forgot.

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