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    QT prolongation Torsades de pointes Alopecia Anaphylactic reactions Angioedema Cholestasis Dizziness Dyspnea Hepatic failure Hepatitis Hypertriglyceridemia Hypokalemia Increased alkaline phosphatase Increased ALT/AST Jaundice Leukopenia Pallor Seizures Stevens-Johnson syndrome Taste perversion Thrombocytopenia Toxic epidermal necrolysis Hypersensitivity to other azoles Use caution in proarrhythmic conditions and renal impairment Use extreme caution or avoid in congenital long-QT patients and patients with conditions that increase QT-prolongation risk Fluconazole inhibits CYP2C9, CYP2C19, and CYP3A4 isoenzymes; coadministration with drugs that are substrates if these isoenzymes may be contraindicated or warrant dosage modifications Capsules contain lactose and should not be given to patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption Powder for oral suspension contains sucrose and should not be used in patients with hereditary fructose, glucose/galactose malabsorption or sucrase-isomaltase deficiency Syrup contains glycerol; may cause headache, stomach upset, and diarrhea Hepatotoxicity reported with use; use with caution in patients with hepatic impairment Rare exfoliative skin disorders reported; monitor closely if rash develops and discontinue if it progresses When driving vehicles or operating machines, it should be taken into account that dizziness or seizures may occasionally occur Candida krusei is inherently resistant Convenience and efficacy of single dose oral tablet of fluconazole regimen for the treatment of vaginal yeast infections should be weighed against acceptability of higher incidence of drug related adverse events with fluconazole (26%) versus intravaginal agents (16%) If drug is used during pregnancy or if patient becomes pregnant while taking the drug, patient should be informed of potential hazard to fetus; effective contraceptive measures should be considered in women of child-bearing potential who are being treated with 400 to 800 mg/day and should continue throughout the treatment period and for approximately 1 week (5 to 6 half-lives) after the final dose Highly selective inhibitor of fungal cytochrome P-450-dependent enzyme lanosterol 14-alpha-demethylase Subsequent loss of normal sterols correlates with accumulation of 14 alpha-methyl sterols in fungi and may be responsible for the fungistatic activity of fluconazole Additive: TMP-SMX Y-site: Amphotericin B, amphotericin B cholesteryl sulfate, ampicillin, calcium gluconate, cefotaxime, ceftazidime(? ), ceftriaxone, cefuroxime, chloramphenicol, clindamycin, co-trimoxazole, diazepam, digoxin, erythromycin lactobionate, furosemide, haloperidol, hydroxyzine, imipenem/cilastatin, pentamidine, piperacillin, ticarcillin, TMP-SMX Solution: D5W, LR Additive: Acyclovir, amikacin, amphotericin B, cefazolin, ceftazidime, ciprofloxacin, clindamycin, gentamicin, heparin, meropenem, metronidazole, morphine, piperacillin, potassium chloride, ranitidine with ondansetron, theophylline Y-site: Acyclovir, aldesleukin, allopurinol, amifostine, amikacin, aminophylline, amiodarone, ampicillin-sulbactam, aztreonam, benztropine, bivalirudin, cefazolin, cefepime, cefotetan, cefoxitin, cefpirome, chlorpromazine, cimetidine, cisatracurium, dexamethasone sodium phosphate, dexmedetomidine, diltiazem, diphenhydramine, dobutamine, docetaxel, dopamine, doxorubicin liposomal, droperidol, etoposide PO4, famotidine, fenoldopam, filgrastim, fludarabine, foscarnet, ganciclovir, gatifloxacin, gemcitabine, gentamicin, granisetron, heparin, hetastarch, hydrocortisone, immune globulin, leucovorin, linezolid, lorazepam, melphalan, meperidine, meropenem, metoclopramide, metronidazole, midazolam, morphine, nafcillin, nitroglycerin, ondansetron, oxacillin, paclitaxel, pancuronium, penicillin G, phenytoin, piperacillin-tazobactam, prochlorperazine, promethazine, propofol, quinupristin-dalfopristin, ranitidine, remifentanil, sargramostim, tacrolimus, teniposide, theophylline, thiotepa, ticarcillin-clavulanate, tobramycin, vancomycin, vecuronium, vinorelbine, zidovudine Tablets: Store below 86° F (30° C) Dry powder: Store below 86° F (30° C); reconstituted suspension should be stored between 86° F (30° C) and 41° F (5° C), and unused portion should be discarded after 2 weeks; protect from freezing Injection (glass bottles): Store between 86° F (30° C) and 41° F (5° C); protect from freezing Injection (Viaflex Plus plastic containers): Store between 77° F (25° C) and 41° F (5° C); protect from freezing The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. metformin resistance Read the Patient Information Leaflet if available from your pharmacist before you start taking fluconazole and each time you get a refill. If you have any questions, ask your doctor or pharmacist. Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are taking the liquid suspension form of this medication, shake the bottle well before each dose. Carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Dosage is based on your medical condition and response to treatment. Generally in children, the dose should not exceed 600 milligrams daily unless directed by the doctor.

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    Wählen Sie eines der folgenden Kapitel aus, um mehr über "FLUCONAZOL STADA 150 mg Hartkapseln" zu erfahren. Je nach Wirkstoffkonzentration werden die Pilze dadurch in ihrem Wachstum und ihrer Vermehrung gehemmt oder sie sterben durch zusätzliche Schädigungen des Zellinneren direkt ab. Die Informationen zu den Wirkstoffen können im Einzelfall von den Angaben im Beipackzettel mancher Fertigarzneimittel abweichen. - Pilzinfektionen, vor allem mit Hefepilzen (Candida oder Kryptokokken), wie: - Pilzinfektionen der inneren Organe oder des ganzen Körpers, wie: - Pilzbefall des Blutes (Candidämie) - Pilzinfektionen des Bauchraumes - Pilzinfektionen der Lunge - Pilzinfektionen der Blase und der Harnwege - Pilzvorkommen im Urin (Candidurie) - Pilzinfektionen oberflächlicher Schleimhäute, wie: - Pilzinfektionen der Speiseröhre - Pilzinfektionen im Mund-Rachenraum, die immer wiederkehren - Pilzinfektionen in der Mundhöhle (Soor), die mit Rückgang der Mundschleimhaut einhergeht (vor allem bei Zahnprothesenträgern) - Pilzinfektionen der Schleimhäute der oberen Luftwege- Pilzinfektion der Hirnhäute (Kryptokokken-Meningitis)- Vorbeugung gegen Wiederauftreten einer Pilzinfektion der Hirnhäute, vor allem bei AIDS-Patienten- Vorbeugung gegen Pilzinfektionen bei Abwehrschwäche, bedingt durch Krankheit (AIDS, Krebserkrankungen) oder Behandlung mit abwehrunterdrückenden Medikamenten wie z. Cortison, Chemotherapie Zur innerlichen Behandlung, wenn eine äußerliche Therapie nicht ausreichend ist:- Pilzinfektionen mit Hefepilzen, Fadenpilzen und anderen Pilzen, wie: - Pilzinfektionen der Scheide, vor allem durch Hefepilze (Candida) - Pilzinfektionen der Haut - Fußpilz - Hautflechte durch Kleienpilz (Pityriasis versicolor) Beschreibt, welche Erkrankungen oder Umstände gegen eine Anwendung des Arzneimittels sprechen, in welchen Altersgruppen das Arzneimittel nicht eingesetzt werden sollte/darf und ob Schwangerschaft und Stillzeit gegen die Anwendung des Arzneimittels sprechen. Immer:- Überempfindlichkeit gegen die Inhaltsstoffe Unter Umständen - sprechen Sie hierzu mit Ihrem Arzt oder Apotheker:- Herzrhythmusstörungen, wie: - Abweichung im EKG (Verlängerung der QT-Dauer), die Herzrhythmusstörungen zur Folge haben kann- Pulserniedrigung- Herzschwäche- Eingeschränkte Leberfunktion- Störungen des Salzhaushaltes, wie: - Kaliummangel - Magnesiummangel- Frauen mit Kinderwunsch oder ohne sicheren Empfängnisschutz Welche Altersgruppe ist zu beachten? Das liegt beispielsweise daran, dass wirkstoffgleiche Präparate von verschiedenen Herstellern für unterschiedliche Anwendungsgebiete zugelassen sind. Der Wirkstoff greift in den Stoffwechsel der Pilze ein, es kommt zu vielen Schäden in der Struktur der Pilze. - Kinder unter 6 Jahren: Das Arzneimittel sollte in dieser Gruppe in der Regel nicht angewendet werden. Diese Hülle verliert somit einen Teil ihrer Funktionen, sie wird z. für Nährstoffe undurchlässiger - die Zelle hungert. Es gibt Präparate, die von der Wirkstoffstärke und/oder Darreichungsform besser geeignet sind.- Kinder unter 16 Jahren: Das Arzneimittel sollte in dieser Altersgruppe in der Regel nicht angewendet werden. - Schwangerschaft: Das Arzneimittel sollte nach derzeitigen Erkenntnissen nicht angewendet werden.- Stillzeit: Von einer Anwendung wird nach derzeitigen Erkenntnissen abgeraten. Ist Ihnen das Arzneimittel trotz einer Gegenanzeige verordnet worden, sprechen Sie mit Ihrem Arzt oder Apotheker. Der therapeutische Nutzen kann höher sein, als das Risiko, das die Anwendung bei einer Gegenanzeige in sich birgt. - Magen-Darm-Beschwerden, wie: - Übelkeit - Erbrechen - Bauchschmerzen - Durchfälle - Verstopfung - Blähungen- Geschmacksstörungen- Mundtrockenheit- Appetitlosigkeit- Kopfschmerzen- Schwindel- Schlaflosigkeit- Schläfrigkeit- Benommenheit- Zittern- Krampfanfälle- Missempfindungen- Überempfindlichkeitsreaktionen der Haut, wie: - Juckreiz - Hautausschlag - Nesselausschlag- Schwitzen- Nierenfunktionsstörungen, mit Veränderungen der Nierenwerte (wie Kreatinin, Harnstoff)- Leberschäden (von vorübergehendem Anstieg der Leberwerte bis zu Gelbsucht, Hepatitis, Leberversagen), die sich z. durch folgende Anzeichen äußern können: - Anstieg der Leberwerte- Anämie (Blutarmut)- Muskelschmerzen- Fieber- Allgemeine Schwäche Bemerken Sie eine Befindlichkeitsstörung oder Veränderung während der Behandlung, wenden Sie sich an Ihren Arzt oder Apotheker. Für die Information an dieser Stelle werden vor allem Nebenwirkungen berücksichtigt, die bei mindestens einem von 1.000 behandelten Patienten auftreten. - Das Arzneimittel darf nicht vorzeitig abgesetzt werden, weil sonst mit einem (erneuten) Ausbruch der Krankheit zu rechnen ist.- Vorsicht bei Allergie gegen Pilzmittel (z. Fluconazol, Voriconazol, Posaconazol, Itraconazol)! - Vorsicht bei einer Unverträglichkeit gegenüber Lactose. It comes as a tablet or suspension you take by mouth. Fluconazole oral tablet is available as both a generic drug, and as the brand-name drug Diflucan. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Fluconazole is used to prevent and treat candidiasis. This condition is caused by infection with one of the many types of the fungus Examples of candidiasis include vaginal yeast infection, as well as oral yeast infection (thrush). Candidiasis can also cause infections on other parts of your body, including your throat, esophagus, lungs, and blood.

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